Platelet Rich Plasma (PRP treatment)
PRP is an exciting non-surgical therapeutic option for male and female patients who require stimulation of hair growth for hair loss conditions.
How does PRP work?
Human blood contains mesenchymal stem cells and autologous blood products that contain essential and specific growth factors that assist in tissue regeneration and healing. PRP therapy has established itself to be effective as a medical treatment modality in the specialty fields of oral surgery, neurosurgery, plastic and cosmetic surgery, sports medicine and orthopedics. It has been used extensively in these specialties for the last two decades with generally positive outcomes and success. In the field of hair restoration, existing evidence demonstrates PRP therapy as a promising treatment option to promote hair growth.
PRP contains special cells called Platelets, that can cause growth of the hair follicles by stimulating the stem cells located in the Dermal Papilla as well as other structures of the hair follicle. These special Platelet cells promotes healing, accelerates the rate and degree of tissue healing and regeneration, response of the body to injury, and formation of new cellular growth. The primary purpose of using PRP in hair restoration is to stimulate inactive or newly implanted hair follicles into an active growth phase.
Growth factors released from activated platelets for hair regrowth:
- Platelet-Derived Growth Factor (PDGF)—promotes blood vessel growth, cell replication, skin formation;
- Transforming Growth-Factor-Beta (TGF-b)—promotes growth of matrix between cells, bone metabolism;
- Vascular Endothelial Growth Factor (VEGF)—promotes blood vessel formation;
- Epidermal Growth Factor (EGF)—promotes cell growth and differentiation, blood vessel formation, collagen formation;
- Fibroblast Growth Factor-2 (FGF-2)—promotes growth of specialized cells and blood vessel formation; and,
- Insulin Like Growth Factor – (IGF)—a regulator of normal physiology in nearly every type of cell in the body.
HOW DO WE PERFORM THE PROCEDURE?
Blood is drawn in our clinic as though you are having routine blood testing at your lab. The blood is spun in a centrifuge and the PRP is separated and removed from the rest of the blood. After centrifugation, the platelets and other vital growth proteins raise to the top of the tube. Under a topical anesthesia, a special micro needling roller device is used to stimulate the dermis of the scalp. This micro needling stimulation causes microtrauma to the dermis that induces other healing and growth repair cells into action. The highly concentrated platelet rich plasma (PRP) is then injected into the scalp and topically.
PRP therapy is done every month for about 4 to 6 sessions for optimal hair regrowth.
PRP can also be used preoperatively, intraoperatively, or post operatively in hair transplant.